Synthesis of silver nanoparticles using peganum harmala. Antibacterial and antifungal activity from seed extracts of peganum harmala, international journal of advance research, ideas and innovations in technology, apa jayaprakash chinnappan, veeran mohanraj 2016. Antibacterial activity of espand peganum harmala alcoholic extracts against six pathogenic bacteria in planktonic 111of p. Pdf antibacterial activity of different parts of peganum. Zygophyllaceae is one of the most famous medicinal plants used in traditional medicine of iraq. Its subdisciplines are virology study of viruses, bacteriology study of bacteria. Its common englishlanguage name came about because of a resemblance to rue. The methanolic fraction was found to be most effective against all. Antimicrobial effect, biofilm, peganum harmala, pathogenic bacteria. Isoelectric focusing polyacrylamide gel electrophoresis analysis showed that the isoelectric point of php was. One streptococcal species of bacteria that has been attributed as the cause streptococcosis in. Study of the chemical components of peganum harmala and.
Bioassaydirected isolation and evaluation of harmine from the terrestrial plant peganum harmala l. The seeds of this plant possess antibacterial activity against drugresistant bacteria, smoke from the seeds kills algae, bacteria, intestinal parasites and mold and the roots are used to kill lice and insects. Antimicrobial activity antibacterial activity introduction the science dealing with the study of the prevention and treatment of diseases caused by microorganisms is known as medical microbiology. International journal of infection antifungal effect of. A nuclear magnetic resonance nmr based metabolomics method was used to identify differential metabolites of methanol extracts obtained from six parts of peganum harmala l. Antimicrobial activity of polyphenols and alkaloids in. Pharmacological and therapeutic effects of peganum harmala. Results were encouraging antj proved the antibacterial, antifungal, antipruritic and probably antiprotozoal effects of the extract, from the department of dermatology. Peganum harmala syrian rue seeds contain approximately 3% 26% harmaline, harmine, and other harmala alkaloids shulgin 1997. Pdf antibacterial activities of peganumharmala harmal. It was found that there is no correlation between phenolic content and antibacterial activity, similar results were obtained by turkmen et al.
The antibacterial activity of peganum harmala extract is found to be comparable with that of 525% sodium hypochlorite on the enterococcus faeclis biofilm. Chemical composition, antibacterial and phytotoxic. Results showed the ethanolic extract of peganum harmala at 0. Alkaloids from the seeds of peganum harmala showing. Previous studies demonstrated that the polyphenols such as tannins and flavonoids as epigallocatechin, catechin, myricetin. The extract of peganum harmala rutaceae was used topically to treat certain cjermatoses of inflammatory nature. In this study, the plant peganum collected for providing its ethanolic and aquatic extract. Ethyl acetate, chloroform, butanol, and methanol extracts from the aerial part of peganum harmala were tested for antibacterial, antioxidant, and antiviral activities. Phytochemical screening, total phenolics and biological. Zygophyllaceae is one of the most famous medicinal plants used in traditional medicine of iran. The present study was carried out to determine the potential antibacterial effect of ethanol extracts of p. Peganum harmala dedicated to the spirit of syrian rue duration. Materials and methods glucose level 280 mgdl were considered 2.
This study was aimed to examine the antibacterial activities of peganum harmala extracts on the. Antibacterial, antiviral and antioxidant activities of. The hypoglycemic effects of an ethanol extract of peganum. Darabpour e, poshtkouhian b, motamedi h, seyyed nejad sm. The harmal methanolic extracts were found to inhibit mycelial radial growth of both fungi. The results show that 8 strains and the secondary metabolites of 10 strains presented antibacterial activities to at least one of the tested bacteria of which. The present study compared the antimicrobial activity of ethanolic extract of peganum harmala l. Green synthesis of assembled silver nanoparticles in nano. Author links open overlay panel d prashanth s john. Eleutherine palmifolia pdf new pdf download service. No significant difference was reported between peganum harmala extract and sodium hypochlorite groups p0. Quinazoline alkaloid, vasicinone 3, showed a vasorelaxant activity against phenylephrineinduced contraction of. African journal of microbiology research antibacterial.
Peganum harmala is used as an analgesic and antiinflammatory agent. Harmine 1 and harmaline 2 showed a moderate in vitro antiplasmodial activity against plasmodium falciparum. The objective of this work is insufficient information on the study of plants p. Green synthesis of assembled silver nanoparticles in nano capsules of peganum harmala l leaf extract. It is effective for the treatment of dermatosis disease 9, its leaves are used as an antinociceptive 10. Peganum harmala seeds are commonly used as a shortacting reversible maoi in combination with dmt or dmtcontaining plants. Abstractin this study, we investigated the synthesis of silver nanoparticles using peganum harmala water extract at ambient temperature. Peganum harmala seed extract has been frequently reported to possess antibacterial potential through in vivo studies. Automator convert ppt to pdf new pdf download service. It has been showed that seed and root extracts of p.
Green synthesis and bactericidal activities of isotropic. Two multivariate statistical analysis methods, principal component analysis pca and partial least squaresdiscriminant analysis plsda. Peganum harmala has antibacterial activity, including antibacterial activity against drugresistant bacteria. Shape, size, and homogeneity affect the biological activity of gold nanoparticles aunps in nanomedicine and catalytic applications. Antibacterial and antifungal activity from seed extracts. Antibacterial activities of peganum harmala harmal seeds extract and fractions against pathogenic e.
Microbial biofilms have attracted interest in recent years because they have become the most important cause of nosocomial infections. Microbial biofilms have attracted interest in recent years because they have become the most important cause of nosocomial. Antimicrobial activity of harmal plant peganum harmala l. The purpose of the current study was to investigate the biofilm formation in shigella flexneri clinical isolates and to evaluate the antibiofilm properties of p. Study on antibacterial activities of endophytic fungi from. A novel antifungal protein, designated as php, was isolated from the seeds of peganum harmala, by cationic exchange chromatography on resource s column and gel filtration on sephadex 75 10300 gl column. Peganum harmala, commonly called wild rue, syrian rue, african rue, esfand, or harmel, among other similar pronunciations and spellings, is a perennial, herbaceous plant, with a woody underground rootstock, of the family nitrariaceae, usually growing in saline soils in temperate desert and mediterranean regions. The methanolic fraction was found to be most effective against all tested microorganisms. Here we biosynthesized monodispersed isotropic and polydispersed anisotropic spherical aunps from leaf and seed extract broths of the medicinal plant peganum harmala l. The ag nanoparticles agnps were characterized by ultravioletvisible spectroscopy uvvis, fourier transform infrared spectroscopy ftir, powder xray diffraction xrd, scanning electron microscopy sem, energy dispersive xray. Peganum harmala, fluoresces under ultraviolet light. Comparing the antibacterial effect of peganum harmala. The base is optically inactive although the isolation of form from the fresh leaves of a. To address this problem, medicinal plants have received the attention of researchers due to the various active compounds they contain.
Bioassayguided purification from the seeds of peganum harmala led to the isolation of harmine 1, harmaline 2, vasicinone 3, and deoxyvasicinone 4. In vitro antibacterial activity results were summarized in table 3 of peganum harmala and its alkaloids against some pathogenic bacterial strains isolated from patients streptococcus. The present study was designed to evaluate the possible neuroprotective activity of ginkgo biloba gb and or peganum harmala ph extract against ad in a rat model. Antibacterial and antifungal activity from seed extracts of peganum harmala. Journal of analytical methods in chemistry hindawi. Successive petroleum ether, chloroform and methanol extracts of peganum harmala seeds were tested in vitro for their antibacterial activity. Peganum harmala, international journal of dermatology 10. Ad was induced by chronic administration intraperitoneal injection of scopolamine 0. Materials and method agar diffusion technique and micro broth dilution method were employed to test the antimicrobial effects of these two agents on s. Purification and characterization of a novel antifungal. The antibacterial activity was evaluated by the determination of minimum inhibitory concentration mic using the solid medium technique. The present study investigated the antimicrobial activity of harmal peganum harmala aqueous extracts against two fungi aspergillus niger and penicilium italicum and two gram negative bacteria escerichia coli and salmonella typhi. In vitro antibacterial activity of several plant extracts. Peganum harmala has been shown to have antibacterial and antiprotozoal activity, including antibacterial activity against drugresistant bacteria 7.
Antibacterial activities of peganumharmala harmal seeds against pathogenic e. Activity of peganum harmala extract against antibiotic. The current study was designed to evaluate the antibacterial activity of o. This study aims to determine the antioxidant and the antimicrobial activity of methanol extract of two plant species widely used in. Antibacterial activity and conjugate investigation. Assessment of the antimicrobial and antioxidant activities. Recent years of research has demonstrated different pharmacological and therapeutic effects of p. Recently, the intensive use of drugs created several side effects one among which is the microbial resistance. The aim of this study was to consider antibacterial effects of the methanolic. Pdf antibacterial activity of espand peganum harmala.
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